Due to the changed structure of the mutant neural protein is cleaved into fragments of increased toxicity.
Alzheimer’s disease occurs more often in older people over 65 years of age, however, it is sometimes diagnosed in people 40 years old or even younger. Approximately 10-15% of these “premature” cases is the result of an inherited genetic predisposition. One such family is called the Australian mutations (as described for the first time in Australia). To understand the essence of it, you need to remember how to develop Alzheimer’s disease.